Silvio O. Conte Digestive Diseases Research Core Centers (P30 Clinical Trial Optional) | RFA DK 18 001

Opportunity Information: Apply for RFA DK 18 001

The Silvio O. Conte Digestive Diseases Research Core Centers (DDRCCs) grant opportunity (Funding Opportunity Number RFA-DK-18-001) is a National Institutes of Health (NIH) center-based funding mechanism administered by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) within the U.S. Department of Health and Human Services. It uses the P30 core center grant mechanism and is labeled "Clinical Trial Optional," meaning the center itself may include clinical trial-related activities when appropriate, but the primary emphasis is on building shared infrastructure and services that strengthen and coordinate an existing portfolio of digestive and liver disease research rather than funding a single stand-alone project.

At its core, this program is designed to bring together groups of basic science and clinical investigators who are already conducting research in digestive and/or liver diseases, and to make their collective work more effective by improving communication, collaboration, and day-to-day research efficiency. Instead of supporting many separate, duplicative resources across individual laboratories or departments, a DDRCC supports shared "core" resources that multiple investigators can use. The idea is that centralized services, facilities, expertise, and administrative coordination can raise overall productivity, accelerate progress, and spark new research directions by making it easier for investigators to work across disciplines and share tools, data, and methods in a cost-effective way.

Each proposed DDRCC must be organized around a clearly defined central theme that reflects the shared scientific focus of the center members in digestive or liver disease research. That theme is not just a label; it is meant to serve as the organizing principle for the center, shaping what kinds of cores are proposed, which investigators are served, and how the center will create synergy across projects. Importantly, the theme must fit squarely within NIDDK's primary mission areas. Applicants are expected to avoid themes that fall primarily under the purview of other NIH Institutes or Centers, since those areas are generally expected to seek primary NIH support elsewhere.

The opportunity is categorized as a discretionary grant in the Food and Nutrition and Health activity area and is associated with CFDA number 93.847. The announcement anticipates a small number of awards (an expected total of 3), indicating a competitive process focused on a limited set of highly cohesive, well-justified centers. The listed award ceiling is $750,000, which signals the program is intended to fund substantial shared infrastructure and coordination, but within a defined budget that encourages applicants to prioritize the most broadly useful and high-impact cores.

Eligibility is broad and includes many types of organizations that can credibly assemble a research community around digestive and liver diseases. Eligible applicants include public and private institutions of higher education, nonprofit organizations (including both 501(c)(3) and non-501(c)(3) entities), for-profit organizations (including small businesses and other than small businesses), and various governmental and quasi-governmental entities such as state, county, and city governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities. It also includes Native American tribal governments (federally recognized) and tribal organizations (other than federally recognized tribal governments), along with an "Other" category subject to additional eligibility details in the full announcement.

From a timing standpoint, the FOA was created on December 5, 2017, with an original closing date of March 7, 2019. Overall, the program is best understood as an NIH-supported hub model for digestive and liver disease research: it funds shared cores and center organization that enable a community of investigators to do better science together than they could do separately, with an explicit requirement that the center theme align with NIDDK mission priorities.

• The Department of Health and Human Services, National Institutes of Health in the food and nutrition, health sector is offering a public funding opportunity titled "Silvio O. Conte Digestive Diseases Research Core Centers (P30 Clinical Trial Optional)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847.
• This funding opportunity was created on Dec 05, 2017.
• Applicants must submit their applications by Mar 07, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $750,000.00 in funding.
• The number of recipients for this funding is limited to 3 candidate(s).
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).

Apply for RFA DK 18 001

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