Continuity of HIV Services during Public Health Emergency Response in High Risk Areas in the Republic of Mozambique under the President's Emergency Plan for AIDS Relief (PEPFAR) | CDC RFA GH21 2154

Opportunity Information: Apply for CDC RFA GH21 2154

This funding opportunity, titled "Continuity of HIV Services during Public Health Emergency Response in High Risk Areas in the Republic of Mozambique under PEPFAR" (CDC RFA GH21-2154), is a CDC cooperative agreement designed to help Mozambique keep core HIV and TB services running when emergencies disrupt normal health operations. The focus is on building and sustaining a stable service delivery platform so that prevention, testing, treatment, and support services for people living with HIV (and TB-related services closely linked to HIV programs) can continue with minimal interruption, even in areas facing repeated shocks such as climate-related disasters, displacement, or political insecurity. The opportunity sits within PEPFAR priorities and is framed around protecting clinical and public health systems that are frequently at risk of disruption.

The program anticipates approximately $15,000,000 in total funding for Year 1, depending on the availability of funds, and expects to make up to two awards. While the notice lists an "award ceiling" of $0 for Year 1, the narrative makes clear that CDC is planning for a substantial Year 1 funding level overall, which is a common way some federal notices present ceiling information while still providing an estimated total amount available. The funding instrument is a cooperative agreement, meaning CDC is expected to have substantial involvement beyond simply providing funds; awardees should expect ongoing technical collaboration, performance monitoring, and alignment with CDC/PEPFAR strategies and reporting requirements. The CFDA (assistance listing) number is 93.067, and eligibility is listed as unrestricted (open to any type of entity), subject to any additional eligibility details included in the full notice.

Programmatically, the NOFO emphasizes interventions that maintain comprehensive, evidence-based HIV and TB prevention, care, support, and treatment in high-risk geographic zones. Rather than focusing only on direct clinical service delivery, the opportunity highlights the systems and enabling functions that keep services operational during instability. Key supported areas include human resources for health (HRH), including staffing models and support that help facilities continue functioning when personnel are stretched thin or systems are disrupted; care and treatment (C&T) for people living with HIV (PLHIV), which typically includes continuity of antiretroviral therapy, retention support, and practical adaptations to keep patients engaged during displacement or access barriers; and TB-related services integrated with HIV programming, reflecting the clinical reality that TB prevention, screening, diagnosis, and treatment are essential components of HIV care in many settings.

The scope also explicitly includes gender-based violence (GBV) and positive health, dignity, and prevention (PHDP). In practice, that signals attention to the social and behavioral dimensions that affect HIV outcomes during crises: GBV risk can increase during displacement and instability, while PHDP approaches help clients reduce onward transmission risk, maintain treatment adherence, and protect wellbeing. In addition, the opportunity calls out broader health system strengthening functions, such as improving service delivery resilience, strengthening coordination and management practices, and reinforcing operational capacity so that clinics and district/provincial health structures can keep essential services functioning. Laboratory support and data quality assessments are also included, pointing to the need to protect the diagnostic and monitoring backbone of HIV/TB programs (for example, ensuring access to and reliability of testing and results, and maintaining dependable data systems even during emergency response conditions). Health communication is listed as another priority area, reflecting the need for clear, timely communication with communities and clients when services move, schedules change, supply chains are disrupted, or public health guidance shifts.

A central expectation for recipients is to provide technical assistance and capacity building to Mozambique government institutions and other stakeholders involved in delivering primary health care and public health services, with a particular emphasis on HIV and TB programs. This is described as multi-level work spanning national, provincial, district, and sub-district levels. That multi-tiered approach suggests recipients will need to coordinate across the health system, tailoring support to central policy and planning needs while also strengthening implementation capacity close to the point of service delivery. The overall intent is not only to respond during an emergency, but to leave behind stronger, more resilient systems and partners who can maintain continuity of care through future disruptions.

Geographically, implementation is targeted to high-risk zones across Mozambique that are prone to instability and displacement, whether driven by climate-related disasters (such as storms, flooding, or other severe weather events) or political insecurity. The emphasis on these settings underscores that the goal is service continuity under difficult, rapidly changing conditions, where patient displacement, facility damage, supply interruptions, staffing shortages, and breakdowns in routine communications can quickly undermine HIV and TB program outcomes. The NOFO is essentially about protecting gains in HIV epidemic control by making sure prevention and treatment services do not collapse during emergencies, and by ensuring that PEPFAR service delivery goals remain achievable in the hardest-hit areas.

Administrative details in the source information include the posting timeline (created February 18, 2021) and the original application deadline (April 19, 2021, by 11:59 p.m. Eastern Time for electronic submission). The sponsoring agency is the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), Center for Global Health (CGH).

• The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Continuity of HIV Services during Public Health Emergency Response in High Risk Areas in the Republic of Mozambique under the President's Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
• This funding opportunity was created on Feb 18, 2021.
• Applicants must submit their applications by Apr 19, 2021 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• The number of recipients for this funding is limited to 2 candidate(s).
• Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.

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